- Gavi-backed vaccination efforts delivered over US$30 billion in economic gains in 2025, driven by reduced healthcare expenses and a healthier, more productive workforce.
- Recognizing the value of immunization, low‑income countries contributed a record US$301 million in co‑financing for Gavi‑supported vaccines in 2025.
- Dr. Sania Nishtar, Gavi CEO, said: “When it comes to immunization, the return on investment goes far beyond health, fostering sustainable and inclusive economic growth.”
Geneva, 7 October 2026 – According to Gavi’s annual report released today, vaccine initiatives backed by Gavi, the Vaccine Alliance, produced over US$30 billion in economic benefits in 2025, marking the alliance’s highest annual total to date. These benefits stem from averting illness, death, and long‑term disability, reducing health‑care and societal expenses, and enabling children to attain higher education, which translates into longer, more productive working lives.
In that same year, lower‑income nations contributed a record US$301 million toward Gavi‑supported vaccines via the Alliance’s co‑financing mechanism, which gradually shifts a larger share of vaccine costs to countries as their economies expand. This trend shows that over the past five years, contributions have equaled the total given in the preceding thirteen years, and from 2026 to 2030, implementing countries are expected to finance close to half of their vaccine expenses.
“Governments face tough budget choices, yet when it comes to immunization we know the return on investment reaches far beyond health, driving sustainable and inclusive economic growth,” said Dr. Sania Nishtar, CEO of Gavi, the Vaccine Alliance. “It is encouraging that this year’s data show immunization delivering unprecedented economic returns, and that countries are responding by increasing their investments in immunization programs accordingly.”
Gavi’s Annual Progress Report also shows a record public‑health impact in 2025, with Gavi‑supported programs immunizing over 73 million children and averting more than 2.2 million future deaths—both record annual figures. This brings the Alliance’s fifth strategic period (2021‑2025) to a strong close, surpassing the target of 300 million immunized children by reaching more than 351 million.
Five-Year Progress Overview
From 2021 to 2025, vaccination prevented over 7.8 million future deaths, meeting Gavi’s strategic target and raising the cumulative number of deaths averted since 2000 to more than 23 million. The period also witnessed stronger immunization systems and broader vaccine access. In 2025, the routine immunization coverage gap between Gavi‑supported countries and the rest of the world reached its lowest recorded level. These advances helped avert disease outbreaks, alleviated pressure on health systems, and strengthened global defenses against cross‑border disease threats.
“When children are vaccinated, they are far more likely to grow up healthy, attend school, and build a promising future,” said Catherine Russell, UNICEF Executive Director. “Last year, in partnership with Gavi, we reached more children with routine vaccines than ever before, and we will keep working with our partners to guarantee every child access to life‑saving immunization.”
“Immunization yields tremendous gains in lives saved and diseases prevented, and it also delivers substantial economic benefits,” said Dr. Tedros Adhanom Ghebreyeus, WHO Director‑General. “Countries recognize that the cost of not vaccinating is far too high, whereas the advantages extend to families, communities, economies, and future generations.”
A New Chapter for Immunization
Although Gavi has not yet met its fundraising goal for 2026‑2030, the Alliance remains committed to protecting an additional 500 million children, averting 8–9 million future deaths, cutting under‑five mortality by another 10 %, and generating more than US$100 billion in economic benefits during that period. In the years ahead, Gavi will prioritize reaching children who still miss out on vaccines—especially those in conflict‑affected and humanitarian settings. Central to this effort is the Gavi Leap reform agenda, which aligns support with national priorities, streamlines cooperation, and maximizes the impact of available resources, ensuring that the benefits of immunization continue to be felt by families, health systems, and economies for years to come.
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