49ers Extend Lead to 24-7 as Deebo Samuel Scores Touchdown in Fourth Quarter

The 49ers have built a substantial lead in the fourth quarter after dominating the first three periods. The Rams will need a significant comeback to secure a season‑opening victory.

San Francisco currently leads 24‑7 with 12:57 left on the clock.

San Francisco seized momentum by stopping Matthew Stafford on a quarterback sneak on fourth‑and‑goal from the 1‑yard line with 3:46 remaining in the third quarter. Linebacker Fred Warner and rookie Gracen Halton combined to stuff Stafford short of the goal line.

The call was upheld after replay review.

Following the stand, the 49ers marched 99 yards in 11 plays, capped by a 15‑yard touchdown reception from Deebo Samuel. This marked Brock Purdy’s third touchdown pass of the game, after earlier strikes of 39 yards to Demarcus Robinson and five yards to Mike Evans.

Purdy finished 24 of 32 for 205 yards, throwing one interception.

Overall, San Francisco has outgained Los Angeles 358 yards to 222.

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