Cadence Secures $100 M to Scale AI‑Driven Chronic Care Automation

America remains one of the biggest spenders on healthcare, yet fewer than 30 % of adults with high blood pressure achieve control, and less than 10 % of heart‑failure patients receive appropriate medications at any given time. The gap reveals a systemic failure in chronic disease management.

Cadence, a New York‑based startup, aims to close this gap by offering an AI‑enabled, continuous‑monitoring platform that operates outside traditional clinic visits. On Tuesday, the company closed a $100 million Series C round led by Spark Capital, bringing its total capital raised to $241 million. The round also attracted Thrive Capital, General Catalyst, Coatue, B Capital, and the venture arm of three health systems: Corewell Health, Memorial Hermann, and Duke Health.

Founded in 2020 by CEO Chris Altchek, Cadence’s mission is to shift chronic‑disease care from episodic clinic encounters to proactive home‑based management. Patients receive connected devices that track vitals in real time, while the platform employs artificial intelligence to anticipate adverse events such as strokes and heart attacks.

“The current model—just a few visits a year—doesn’t work,” Altchek explained. “At Cadence we flip that paradigm, delivering personalized, data‑driven care around the clock.”

The company operates its own clinical practice with over 300 staff, including physicians, nurses, and nurse practitioners. When partnered with health systems, Cadence’s team is white‑labelled under the partner’s brand and delivers care according to the system’s clinical protocols.

Cadence already serves more than 100 000 patients across a portfolio of health‑system partners, including Providence, Yale New Haven Health, Hackensack Meridian Health, Lifepoint Health, Community Health Systems, Hartford HealthCare, and Rush University System for Health.

With a new valuation of $1.23 billion, the founders view the investment by AI‑savvy backers—including Spark Capital, known for Anthropic, and Thrive Capital, an early supporter of OpenAI—as validation that artificial intelligence can have a profound, positive impact on chronic‑care outcomes.

“AI isn’t about job displacement; it’s about making people healthier,” Altchek stated. “We’re an example of that happening now.”

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